P22T (p.Pro22Thr) variant of MAP2K2 (P36507)
P22T (p.Pro22Thr) in MAP2K2 (P36507) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
P22T (p.Pro22Thr) variant details
- p.Pro22Thr
- ExAC rs766829845
- gnomAD rs766829845
- Missense
- Variant Prioritization Score for Impact Estimate 0.44
- REVEL 0.27
- CADD 21.40
- PolyPhen-2 0.00
- SIFT 0.35
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available