P22L (p.Pro22Leu) variant of MAP2K2 (P36507)
P22L (p.Pro22Leu) in MAP2K2 (P36507) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
P22L (p.Pro22Leu) variant details
- p.Pro22Leu
- gnomAD rs1325938060
- Missense
- Variant Prioritization Score for Impact Estimate 0.447
- REVEL 0.35
- CADD 22.90
- PolyPhen-2 0.00
- SIFT 0.09
- Population evidence available
- Structural context available