P16L (p.Pro16Leu) variant of MAP2K2 (P36507)
P16L (p.Pro16Leu) in MAP2K2 (P36507) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
P16L (p.Pro16Leu) variant details
- p.Pro16Leu
- TOPMed rs2041335513
- Missense
- Variant Prioritization Score for Impact Estimate 0.381
- REVEL 0.17
- CADD 22.30
- PolyPhen-2 0.09
- SIFT 0.14
- Population evidence available
- Structural context available