N33Y (p.Asn33Tyr) variant of MAP2K2 (P36507)
N33Y (p.Asn33Tyr) in MAP2K2 (P36507) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
N33Y (p.Asn33Tyr) variant details
- p.Asn33Tyr
- Ensembl rs2145080951
- Missense
- Variant Prioritization Score for Impact Estimate 0.401
- REVEL 0.34
- AlphaMissense 0.15
- MetaLR 0.73
- MetaSVM 0.13
- CADD 21.40
- PolyPhen-2 0.47
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available