L12P (p.Leu12Pro) variant of MAP2K2 (P36507)
L12P (p.Leu12Pro) in MAP2K2 (P36507) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
L12P (p.Leu12Pro) variant details
- p.Leu12Pro
- Ensembl rs2145089922
- Missense
- Variant Prioritization Score for Impact Estimate 0.421
- REVEL 0.31
- CADD 25.40
- PolyPhen-2 0.00
- SIFT 0.01
- Population evidence available
- Structural context available