K6N (p.Lys6Asn) variant of MAP2K2 (P36507)
K6N (p.Lys6Asn) in MAP2K2 (P36507) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
K6N (p.Lys6Asn) variant details
- p.Lys6Asn
- Ensembl rs2145090011
- Missense
- Variant Prioritization Score for Impact Estimate 0.416
- REVEL 0.25
- AlphaMissense 0.79
- MetaLR 0.26
- MetaSVM -0.74
- CADD 23.10
- PolyPhen-2 0.05
- Most common in the Non-Finnish European population (allele frequency 9.4e-07)
- Structural context available