K6E (p.Lys6Glu) variant of MAP2K2 (P36507)
K6E (p.Lys6Glu) in MAP2K2 (P36507) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
K6E (p.Lys6Glu) variant details
- p.Lys6Glu
- Ensembl rs2145090022
- Missense
- Variant Prioritization Score for Impact Estimate 0.48
- REVEL 0.45
- AlphaMissense 0.42
- MetaLR 0.30
- MetaSVM -0.54
- CADD 24.40
- PolyPhen-2 0.10
- Population evidence available
- Structural context available