E43G (p.Glu43Gly) variant of MAP2K2 (P36507)
E43G (p.Glu43Gly) in MAP2K2 (P36507) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
E43G (p.Glu43Gly) variant details
- p.Glu43Gly
- gnomAD rs1281225185
- Missense
- Variant Prioritization Score for Impact Estimate 0.636
- REVEL 0.63
- CADD 26.90
- PolyPhen-2 0.99
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available