A29D (p.Ala29Asp) variant of MAP2K2 (P36507)
A29D (p.Ala29Asp) in MAP2K2 (P36507) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
A29D (p.Ala29Asp) variant details
- p.Ala29Asp
- ExAC rs747864035
- gnomAD rs747864035
- Missense
- Variant Prioritization Score for Impact Estimate 0.515
- REVEL 0.40
- CADD 21.80
- PolyPhen-2 0.06
- SIFT 0.28
- Most common in the South Asian population (allele frequency 5e-05)
- Structural context available