A11P (p.Ala11Pro) variant of MAP2K2 (P36507)
A11P (p.Ala11Pro) in MAP2K2 (P36507) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
A11P (p.Ala11Pro) variant details
- p.Ala11Pro
- ExAC rs750214699
- gnomAD rs750214699
- Missense
- Variant Prioritization Score for Impact Estimate 0.508
- REVEL 0.39
- CADD 21.40
- PolyPhen-2 0.00
- SIFT 0.92
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available