Y89C (p.Tyr89Cys) variant of MAOA (P21397)
Y89C (p.Tyr89Cys) in MAOA (P21397) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
Y89C (p.Tyr89Cys) variant details
- p.Tyr89Cys
- TOPMed rs2033551680
- gnomAD rs2033551680
- Missense
- Variant Prioritization Score for Impact Estimate 0.77
- REVEL 0.86
- MetaLR 0.89
- MetaSVM 0.98
- CADD 25.60
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3.2e-05)
- Structural context available