Y100C (p.Tyr100Cys) variant of MAOA (P21397)
Y100C (p.Tyr100Cys) in MAOA (P21397) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
Y100C (p.Tyr100Cys) variant details
- p.Tyr100Cys
- gnomAD X-43693421-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.39
- REVEL 0.37
- MetaLR 0.09
- MetaSVM -1.09
- CADD 27.10
- PolyPhen-2 0.98
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- Literature evidence available