T88I (p.Thr88Ile) variant of MAOA (P21397)
T88I (p.Thr88Ile) in MAOA (P21397) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
T88I (p.Thr88Ile) variant details
- p.Thr88Ile
- ExAC rs768926368
- gnomAD rs768926368
- Missense
- Variant Prioritization Score for Impact Estimate 0.437
- REVEL 0.32
- MetaLR 0.10
- MetaSVM -1.00
- CADD 23.40
- PolyPhen-2 0.85
- SIFT 0.01
- Most common in the East Asian population (allele frequency 3.3e-05)
- Structural context available