T105I (p.Thr105Ile) variant of MAOA (P21397)
T105I (p.Thr105Ile) in MAOA (P21397) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
T105I (p.Thr105Ile) variant details
- p.Thr105Ile
- gnomAD X-43711879-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.208
- REVEL 0.21
- MetaLR 0.52
- MetaSVM -0.50
- CADD 6.04
- PolyPhen-2 0.08
- SIFT 0.07
- Most common in the South Asian population (allele frequency 5.6e-05)
- Structural context available
- Literature evidence available