T105A (p.Thr105Ala) variant of MAOA (P21397)
T105A (p.Thr105Ala) in MAOA (P21397) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
T105A (p.Thr105Ala) variant details
- p.Thr105Ala
- gnomAD rs1309805299
- Missense
- Variant Prioritization Score for Impact Estimate 0.391
- REVEL 0.27
- MetaLR 0.46
- MetaSVM -0.60
- CADD 13.10
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available