I55T (p.Ile55Thr) variant of MAOA (P21397)
I55T (p.Ile55Thr) in MAOA (P21397) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
I55T (p.Ile55Thr) variant details
- p.Ile55Thr
- gnomAD rs1162350391
- Missense
- Variant Prioritization Score for Impact Estimate 0.436
- REVEL 0.38
- MetaLR 0.63
- MetaSVM 0.01
- CADD 18.30
- PolyPhen-2 0.03
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available