G11A (p.Gly11Ala) variant of MAOA (P21397)
G11A (p.Gly11Ala) in MAOA (P21397) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
G11A (p.Gly11Ala) variant details
- p.Gly11Ala
- gnomAD X-43656373-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.31
- REVEL 0.04
- MetaLR 0.02
- MetaSVM -0.96
- CADD 19.60
- PolyPhen-2 0.00
- SIFT 0.27
- Most common in the African/African-American population (allele frequency 3.8e-05)
- Structural context available
- Literature evidence available