F112L (p.Phe112Leu) variant of MAOA (P21397)
F112L (p.Phe112Leu) in MAOA (P21397) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
F112L (p.Phe112Leu) variant details
- p.Phe112Leu
- TOPMed rs2033702607
- gnomAD rs2033702607
- Missense
- Variant Prioritization Score for Impact Estimate 0.279
- REVEL 0.15
- MetaLR 0.02
- MetaSVM -0.98
- CADD 19.30
- PolyPhen-2 0.04
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 3.8e-05)
- Structural context available