D15N (p.Asp15Asn) variant of MAOA (P21397)
D15N (p.Asp15Asn) in MAOA (P21397) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact in the context of in a breast cancer sample. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
D15N (p.Asp15Asn) variant details
- p.Asp15Asn
- rs1268810174
- gnomAD rs1268810174
- Variant assessed as somatic; moderate impact.
- in a breast cancer sample
- Missense
- Variant Prioritization Score for Impact Estimate 0.381
- REVEL 0.19
- MetaLR 0.08
- MetaSVM -1.10
- CADD 28.40
- PolyPhen-2 0.94
- SIFT 0.07
- UniProt: Variant assessed as somatic; moderate impact. (in a breast cancer sample)
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available