P12L (p.Pro12Leu) variant of MALT1 (Q9UDY8)
P12L (p.Pro12Leu) in MALT1 (Q9UDY8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
P12L (p.Pro12Leu) variant details
- p.Pro12Leu
- gnomAD 18-58671678-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.203
- CADD 9.82
- PolyPhen-2 0.05
- SIFT 0.09
- Most common in the South Asian population (allele frequency 0.00016)
- Structural context available
- Literature evidence available