T86I (p.Thr86Ile) variant of MAGED2 (Melanoma-associated antigen D2)
T86I (p.Thr86Ile) in MAGED2 (Melanoma-associated antigen D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
T86I (p.Thr86Ile) variant details
- p.Thr86Ile
- gnomAD X-54809933-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.191
- REVEL 0.04
- CADD 15.60
- PolyPhen-2 0.08
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available