T81S (p.Thr81Ser) variant of MAGED2 (Melanoma-associated antigen D2)
T81S (p.Thr81Ser) in MAGED2 (Melanoma-associated antigen D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
T81S (p.Thr81Ser) variant details
- p.Thr81Ser
- gnomAD X-54809918-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.326
- REVEL 0.04
- CADD 16.30
- PolyPhen-2 0.13
- SIFT 0.09
- Most common in the South Asian population (allele frequency 1.9e-05)
- Structural context available
- Literature evidence available