T81A (p.Thr81Ala) variant of MAGED2 (Melanoma-associated antigen D2)
T81A (p.Thr81Ala) in MAGED2 (Melanoma-associated antigen D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
T81A (p.Thr81Ala) variant details
- p.Thr81Ala
- gnomAD rs1486743215
- Missense
- Variant Prioritization Score for Impact Estimate 0.106
- REVEL 0.02
- CADD 18.00
- PolyPhen-2 0.08
- SIFT 0.05
- Most common in the East Asian population (allele frequency 3.4e-05)
- Structural context available