S24N (p.Ser24Asn) variant of MAGED2 (Melanoma-associated antigen D2)
S24N (p.Ser24Asn) in MAGED2 (Melanoma-associated antigen D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
S24N (p.Ser24Asn) variant details
- p.Ser24Asn
- TOPMed rs1265121302
- Missense
- Variant Prioritization Score for Impact Estimate 0.215
- REVEL 0.02
- CADD 9.61
- PolyPhen-2 0.03
- SIFT 0.16
- Most common in the African/African-American population (allele frequency 3.8e-05)
- Structural context available