R76G (p.Arg76Gly) variant of MAGED2 (Melanoma-associated antigen D2)
R76G (p.Arg76Gly) in MAGED2 (Melanoma-associated antigen D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
R76G (p.Arg76Gly) variant details
- p.Arg76Gly
- TOPMed rs767820484
- Missense
- Variant Prioritization Score for Impact Estimate 0.144
- REVEL 0.05
- CADD 15.90
- PolyPhen-2 0.00
- SIFT 0.08
- Most common in the South Asian population (allele frequency 3.8e-05)
- Structural context available