M27T (p.Met27Thr) variant of MAGED2 (Melanoma-associated antigen D2)
M27T (p.Met27Thr) in MAGED2 (Melanoma-associated antigen D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
M27T (p.Met27Thr) variant details
- p.Met27Thr
- ExAC rs769357290
- gnomAD rs769357290
- Missense
- Variant Prioritization Score for Impact Estimate 0.12
- REVEL 0.03
- CADD 17.50
- PolyPhen-2 0.04
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 2.9e-05)
- Structural context available