K56N (p.Lys56Asn) variant of MAGED2 (Melanoma-associated antigen D2)
K56N (p.Lys56Asn) in MAGED2 (Melanoma-associated antigen D2) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
K56N (p.Lys56Asn) variant details
- p.Lys56Asn
- NCI-TCGA Cosmic COSV5449
- cosmic curated COSV54497
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.286
- REVEL 0.13
- CADD 20.10
- PolyPhen-2 0.97
- SIFT 0.14
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available