A75G (p.Ala75Gly) variant of MAGED2 (Melanoma-associated antigen D2)
A75G (p.Ala75Gly) in MAGED2 (Melanoma-associated antigen D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
A75G (p.Ala75Gly) variant details
- p.Ala75Gly
- ExAC rs781247578
- TOPMed rs781247578
- gnomAD rs781247578
- Missense
- Variant Prioritization Score for Impact Estimate 0.148
- REVEL 0.02
- CADD 18.80
- PolyPhen-2 0.06
- SIFT 0.02
- Most common in the East Asian population (allele frequency 0.00057)
- Structural context available