W84R (p.Trp84Arg) variant of LYST (Lysosomal-trafficking regulator)
W84R (p.Trp84Arg) in LYST (Lysosomal-trafficking regulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
W84R (p.Trp84Arg) variant details
- p.Trp84Arg
- ESP rs150500390
- ExAC rs150500390
- TOPMed rs150500390
- gnomAD rs150500390
- Missense
- Variant Prioritization Score for Impact Estimate 0.649
- REVEL 0.64
- CADD 27.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available