T41S (p.Thr41Ser) variant of LYST (Lysosomal-trafficking regulator)
T41S (p.Thr41Ser) in LYST (Lysosomal-trafficking regulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
T41S (p.Thr41Ser) variant details
- p.Thr41Ser
- ExAC rs749681929
- TOPMed rs749681929
- gnomAD rs749681929
- Missense
- Variant Prioritization Score for Impact Estimate 0.0971
- REVEL 0.05
- CADD 14.50
- PolyPhen-2 0.05
- SIFT 0.06
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available