T41A (p.Thr41Ala) variant of LYST (Lysosomal-trafficking regulator)
T41A (p.Thr41Ala) in LYST (Lysosomal-trafficking regulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
T41A (p.Thr41Ala) variant details
- p.Thr41Ala
- ExAC rs749681929
- TOPMed rs749681929
- gnomAD rs749681929
- Missense
- Variant Prioritization Score for Impact Estimate 0.0876
- REVEL 0.04
- CADD 9.76
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available