S131R (p.Ser131Arg) variant of LYST (Lysosomal-trafficking regulator)
S131R (p.Ser131Arg) in LYST (Lysosomal-trafficking regulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
S131R (p.Ser131Arg) variant details
- p.Ser131Arg
- TOPMed rs1194287259
- gnomAD rs1194287259
- Missense
- Variant Prioritization Score for Impact Estimate 0.141
- REVEL 0.04
- CADD 19.00
- Most common in the HGDP:BURUSHO population (allele frequency 0.042)
- Structural context available