R10H (p.Arg10His) variant of LYST (Lysosomal-trafficking regulator)
R10H (p.Arg10His) in LYST (Lysosomal-trafficking regulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
R10H (p.Arg10His) variant details
- p.Arg10His
- ESP rs145439907
- ExAC rs145439907
- TOPMed rs145439907
- gnomAD rs145439907
- Missense
- Variant Prioritization Score for Impact Estimate 0.506
- REVEL 0.29
- CADD 26.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available