N6S (p.Asn6Ser) variant of LYST (Lysosomal-trafficking regulator)
N6S (p.Asn6Ser) in LYST (Lysosomal-trafficking regulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
N6S (p.Asn6Ser) variant details
- p.Asn6Ser
- gnomAD rs1254846711
- Missense
- Variant Prioritization Score for Impact Estimate 0.435
- REVEL 0.29
- CADD 25.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available