N21S (p.Asn21Ser) variant of LYST (Lysosomal-trafficking regulator)
N21S (p.Asn21Ser) in LYST (Lysosomal-trafficking regulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
N21S (p.Asn21Ser) variant details
- p.Asn21Ser
- gnomAD rs1256066587
- Missense
- Variant Prioritization Score for Impact Estimate 0.303
- REVEL 0.09
- CADD 21.50
- PolyPhen-2 0.11
- SIFT 0.29
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available