K108T (p.Lys108Thr) variant of LYST (Lysosomal-trafficking regulator)
K108T (p.Lys108Thr) in LYST (Lysosomal-trafficking regulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
K108T (p.Lys108Thr) variant details
- p.Lys108Thr
- TOPMed rs1673347955
- gnomAD rs1673347955
- Missense
- Variant Prioritization Score for Impact Estimate 0.407
- REVEL 0.24
- CADD 25.50
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available