I61M (p.Ile61Met) variant of LYST (Lysosomal-trafficking regulator)
I61M (p.Ile61Met) in LYST (Lysosomal-trafficking regulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
I61M (p.Ile61Met) variant details
- p.Ile61Met
- gnomAD rs1675802266
- Missense
- Variant Prioritization Score for Impact Estimate 0.252
- REVEL 0.11
- CADD 18.70
- PolyPhen-2 0.32
- SIFT 0.01
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available