I105V (p.Ile105Val) variant of LYST (Lysosomal-trafficking regulator)
I105V (p.Ile105Val) in LYST (Lysosomal-trafficking regulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
I105V (p.Ile105Val) variant details
- p.Ile105Val
- ExAC rs757904572
- gnomAD rs757904572
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.07
- CADD 18.60
- PolyPhen-2 0.01
- SIFT 0.11
- Population evidence available
- Structural context available