E32G (p.Glu32Gly) variant of LYST (Lysosomal-trafficking regulator)
E32G (p.Glu32Gly) in LYST (Lysosomal-trafficking regulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
E32G (p.Glu32Gly) variant details
- p.Glu32Gly
- cosmic curated COSV67710
- Ensembl rs1675822145
- Missense
- Variant Prioritization Score for Impact Estimate 0.393
- REVEL 0.20
- CADD 29.00
- PolyPhen-2 0.61
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available