D103Y (p.Asp103Tyr) variant of LYST (Lysosomal-trafficking regulator)
D103Y (p.Asp103Tyr) in LYST (Lysosomal-trafficking regulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
D103Y (p.Asp103Tyr) variant details
- p.Asp103Tyr
- ExAC rs765939688
- TOPMed rs765939688
- gnomAD rs765939688
- Missense
- Variant Prioritization Score for Impact Estimate 0.293
- REVEL 0.24
- CADD 23.40
- PolyPhen-2 0.76
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available