p.Pro11dup variant of LRP5 (O75197)
p.Pro11dup in LRP5 (O75197) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data, published literature, and structural context.
p.Pro11dup variant details
- rs1231935129
- gnomAD 11-68312743-G-GGC
- Inframe Insertion
- Variant Prioritization Score for Impact Estimate 0.615
- CADD 7.78
- Most common in the Non-Finnish European population (allele frequency 4.9e-06)
- Structural context available
- Literature evidence available