p.Leu12 Leu13insArgProLeu variant of LRP5 (O75197)

Name: LRP5 p.Leu12 Leu13insArgProLeu variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-21
License: https://catvariant.com/terms-of-use

p.Leu12 Leu13insArgProLeu in LRP5 (O75197) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.

p.Leu12 Leu13insArgProLeu variant details

rs946141296
gnomAD 11-68312742-T-TGG
Inframe Insertion
Variant Prioritization Score for Impact Estimate 0.318
CADD 7.41
Most common in the Non-Finnish European population (allele frequency 1.6e-05)
Structural context available
Literature evidence available