W10R (p.Trp10Arg) variant of LRP5 (O75197)
W10R (p.Trp10Arg) in LRP5 (O75197) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
W10R (p.Trp10Arg) variant details
- p.Trp10Arg
- gnomAD 11-68312742-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.284
- REVEL 0.28
- CADD 7.88
- PolyPhen-2 0.00
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available