P9T (p.Pro9Thr) variant of LRP5 (O75197)
P9T (p.Pro9Thr) in LRP5 (O75197) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
P9T (p.Pro9Thr) variant details
- p.Pro9Thr
- gnomAD 11-68312739-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.261
- REVEL 0.24
- CADD 7.32
- PolyPhen-2 0.64
- SIFT 0.42
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available
- Literature evidence available