P9S (p.Pro9Ser) variant of LRP5 (O75197)
P9S (p.Pro9Ser) in LRP5 (O75197) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
P9S (p.Pro9Ser) variant details
- p.Pro9Ser
- TOPMed rs1285364397
- gnomAD rs1285364397
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.26
- CADD 7.16
- PolyPhen-2 0.64
- SIFT 0.58
- Most common in the East Asian population (allele frequency 0.0002)
- Structural context available