P8Q (p.Pro8Gln) variant of LRP5 (O75197)
P8Q (p.Pro8Gln) in LRP5 (O75197) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
P8Q (p.Pro8Gln) variant details
- p.Pro8Gln
- TOPMed rs2098589225
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.19
- CADD 4.86
- PolyPhen-2 0.00
- SIFT 0.19
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available