P8A (p.Pro8Ala) variant of LRP5 (O75197)
P8A (p.Pro8Ala) in LRP5 (O75197) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
P8A (p.Pro8Ala) variant details
- p.Pro8Ala
- gnomAD 11-68312736-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.22
- CADD 6.29
- PolyPhen-2 0.00
- SIFT 0.49
- Population evidence available
- Structural context available
- Literature evidence available