P6S (p.Pro6Ser) variant of LRP5 (O75197)
P6S (p.Pro6Ser) in LRP5 (O75197) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
P6S (p.Pro6Ser) variant details
- p.Pro6Ser
- gnomAD 11-68312730-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.395
- REVEL 0.25
- CADD 10.30
- PolyPhen-2 0.00
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available