P5T (p.Pro5Thr) variant of LRP5 (O75197)
P5T (p.Pro5Thr) in LRP5 (O75197) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
P5T (p.Pro5Thr) variant details
- p.Pro5Thr
- gnomAD 11-68312727-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.32
- REVEL 0.27
- CADD 19.10
- PolyPhen-2 0.64
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00021)
- Structural context available
- Literature evidence available