P11T (p.Pro11Thr) variant of LRP5 (O75197)
P11T (p.Pro11Thr) in LRP5 (O75197) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
P11T (p.Pro11Thr) variant details
- p.Pro11Thr
- gnomAD 11-68312745-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.31
- REVEL 0.30
- CADD 6.11
- PolyPhen-2 0.64
- SIFT 0.53
- Most common in the Non-Finnish European population (allele frequency 6.1e-06)
- Structural context available
- Literature evidence available